VISTA Cell Reports Paper Featured by Stanford SLAC — Cochran Lab


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VSIG‐3 as a ligand of VISTA inhibits human T‐cell function Wang

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Researchers find VISTA molecule silences immune system against cancer

V-domain Ig suppressor of T cell activation (VISTA) is a novel inhibitory immune-checkpoint protein. VISTA expression on tumour cells and the associated regulatory mechanisms remain unclear..


VISTA Is a Novel BroadSpectrum Negative Checkpoint Regulator for

VISTA (V-domain immunoglobulin suppressor of T cell activation) is a well-established immune regulatory receptor. However, pre-clinical investigations indicated more complicated influences of VISTA on cancer immunity than previously recognized.


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Among the expanding list of T cell inhibitory regulators, V domain immunoglobulin suppressor of T cell activation (VISTA) is a unique B7 family checkpoint that regulates a broad spectrum of.


The expression of VISTA and immune cell infiltration in mouse

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Blocking the interaction between VISTA and VISTAR can lead to T cell

VISTA is a potent negative regulator of T cell function that is expressed on hematopoietic cells and leukocytes. VISTA levels are heightened within the tumor microenvironment where its blockade can enhance anti-tumor immune responses in mice. In humans, blockade of the related PD-1 pathway has shown great potential in clinical immunotherapy trials.


A New VISTA on combination therapy for negative checkpoint regulator

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VISTA A Mediator of Quiescence and a Promising Target in Cancer

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Structure and Functional Binding Epitope of Vdomain Ig Suppressor of T

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Blocking the interaction between VISTA and VISTAR can lead to T cell

As a live yeast product, Vistacell® works to improve intestinal gut health by stabilising the gut microflora and increasing the presence of beneficial bacteria. Evidence indicates that live yeast improves the nutrient composition of sow milk, with higher levels of immunoglobulins in the milk which can help to increase piglet immunity. This can.


The Binding of Human VDomain Ig Suppressor of T Cell Activation

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Mechanism of acquired resistance to antiPD1

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VISTA and Iba1+ cellular subtypes. (a) VISTA expression on the tumor

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